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Image Search Results
Journal: Nucleic acids research
Article Title: Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome.
doi: 10.1093/nar/gkac1238
Figure Lengend Snippet: Figure 3. A3A mRNA expression in human airway and lung cells. (A) The A3A mRNA level in each cell line was quantified by RT–ddPCR 18 h after treatment without (control) or with IFN-ß and/or TNF- under normoxic conditions (N). A549, Calu-3, SAE, AT2 and LBE cells and HNEpCs were also cultured under hypoxic conditions (H). The mean mRNA copy num- bers of A3A relative to those of the housekeeping gene RPP40 are shown (n = 3). (B) The CD11b and CD68 mRNA levels in each untreated cell line were quantified by RT–ddPCR. Human MDMs were used as positive controls. The mean mRNA copy numbers of CD11b and CD68 relative to those of RPP40 are shown (n = 3). The error bars indicate the + SD values.
Article Snippet:
Techniques: Expressing, Control, Cell Culture
Journal: eBioMedicine
Article Title: Underground railway particulate matter and susceptibility to pneumococcal infection
doi: 10.1016/j.ebiom.2022.104063
Figure Lengend Snippet: Effect of 20 µg/mL London Underground particulate matter less than 10 microns from microns from Bakerloo (B-PM 10 ) and Jubilee lines (J-PM 10 ) on human primary epithelial cells. Pneumococcal adhesion to (a) human primary nasal epithelial cells (HPNEpC B-PM 10 and J-PM 10 n=5, technical replicates (TR)=3, p=0.007 and p=0.032, respectively, and (b) primary bronchial epithelial cells (HPBEpC; B-PM 10 and J-PM 10 n=5, TR=3, p=0.017 and p=0.014, respectively). Platelet-activating factor receptor (PAFR) median fluorescence intensity (MFI) expression, (c) HPNEpC (B-PM 10 and J-PM 10 , n=5, TR=2, p= 0.011 and p=0.02, respectively) and, (d) HPBEpC (B-PM 10 and J-PM 10 , n=5, TR=2, p=0.013 and p=0.003, respectively. Columns represents median and p values are calculated by Kruskal-Wallis with post hoc multiple comparison testing.
Article Snippet:
Techniques: Fluorescence, Expressing